The 2021–22 season was the 35th season in the existence of Nîmes Olympique and the club's first season back in the second division of French football. In addition to the domestic league, Nîmes participated in this season's edition of the Coupe de France.
Players
First-team squad
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
^A technical challenge on the outcome of the sixth round game led to the game being ordered to be replayed on 7 November 2021, however the appeal commission overruled the decision, re-instating the original result.[4][5]