The 2021 Kilkenny Senior Hurling Championship was the 127th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board in 1887. The championship began on 2 October 2021 and ended on 7 November 2021.
The final was played on 7 November 2021 at UPMC Nowlan Park in Kilkenny, between Ballyhale Shamrocks and O'Loughlin Gaels, in what was their first meeting in a final in five years. Ballyhale Shamrocks won the match by 3–19 to 3–15 to claim their 19th championship title overall and a fourth title in succession.[2]
T. J. Reid was the championship's top scorer with 1-31.
S Ryan (1-7, 0-6 frees); B Ryan (0-4, 0-1 line-ball); C Murphy (0-2, 0-1 free); B Murphy (1-0); J Roberts (1-0); C Hoyne (0-1, free) and T Dunphy & S Butler (0-1 each).
S Stapleton (0-7, 0-5f), A Gaffney (1-1), A Nolan (1-0), B Sheehan (0-2), C Buckley (0-1, 0-1f), R Fitzpatrick, T Clifford, L Moore and M Nolan (0-1 each).
E Guilfoyle (1-3, 2 frees); N Brassil (0-3, 3 frees); Matt Ruth, C Browne, L Scanlon & C Kenny (2 frees) (0-2 each); T O'Dwyer, C Kenny & M Drennan (0-1 each).