The 2020–21 Grenoble Foot 38 season was the club's 129th season in existence and its third consecutive season in the second flight of French football. In addition to the domestic league, Grenoble participated in this season's edition of the Coupe de France. The season covered the period from 1 July 2020 to 30 June 2021.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.