The 2015–16 season was Cambridge United's 103rd season in their history and their second consecutive season in League Two.[1] Along with League Two, the club also competed in the FA Cup, League Cup and League Trophy. The season covered the period from 1 July 2015 to 30 June 2016.
* Player appearances and goals for the club as of beginning of 2015–16 season.# Date of first team debut
On 21 May 2015, Cambridge United announced they would face Coventry City in as part of their pre-season schedule.[65] On 28 May 2015, Cambridge United announced their second pre-season friendly against Ipswich Town.[66] On 8 June 2015, Norwich City was added to the pre-season fixture list.[67] On 16 June 2015, a date for Chris Turner's memorial match was announced.[68]
On 17 June 2015, the fixtures for the forthcoming season were announced.[69]
On 26 October 2015 the draw for the first round of the FA Cup was drawn and Cambridge United host National League South side Basingstoke Town.[70]
On 16 June 2015, the first round draw was made, Cambridge United were drawn away against Rotherham United.[71]
On 8 August 2015, live on Soccer AM the draw for the first round of the Football League Trophy was drawn by Toni Duggan and Alex Scott. U's host Dagenham & Redbridge.[72]