Roger Federer defeated James Blake in the final, 6–0, 6–3, 6–4 to win the singles tennis title at the 2006 Tennis Masters Cup. It was his third Tour Finals title.[1]
David Nalbandian was the defending champion, but was defeated in the semifinals by Blake.
Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won; 5. steering-committee decision.