The 2006–07 season of the BelgianFirst Division began on July 28, 2006, and concluded on May 19, 2007. The championship was decided in the penultimate round on May 12, 2007, when Anderlecht moved five points clear of runners-up Genk to retain the title and win their 29th League Championship. At the other end of the table, the struggle to avoid automatic relegation went on until the final round, and it was Lierse who eventually prevailed. Having spent the entire season at the bottom of the standings and only just managing to close an eleven-point gap up to 17th, the Lier side won their last game to climb past Beveren and send the latter down to the Second Division. However, Lierse went on to lose the playoffs and was relegated anyway.
Clubs
Eighteen teams played in the 2006-07 first division. Twelve teams were from Flanders, four clubs from Wallonia and just two clubs from the Brussels-Capital Region.
November 7 - Thomas Caers quits his job as manager of Sint Truiden as he feels the players don't respect him anymore after a series of bad results.
November 13 - René Trost agrees with the management of Lierse to split up and each go their own way. At that time Lierse is in last position, with two points out of 12 matches.
March 19 - Marc Brys announces he will finish the season as trainer at K.F.C. Germinal Beerschot, but will then quit his job. No new trainer is announced to replace him.
April 15 - At Lokeren, assistant coach Rudy Cossey announces he will leave the club after 12 years and take up the job of head coach at second division team Oud-Heverlee Leuven next season. In Leuven, Guido Brepoels had announced a few weeks earlier that he was leaving at the end of the season to take up the job at another second division team, KVSK United.
April 20 - Ariël Jacobs, head coach at Mouscron, is named by many sources to become the new assistant coach of Franky Vercauteren at Anderlecht next season. Glen De Boeck, his assistant coach at that time, is applying for a job at Cercle Brugge. Franky Van der Elst is doing the same thing and a decision concerning the new coaching team of Cercle Brugge for the new season is said to be announced soon.
April 26 - Club Brugge announces that Charleroi coach Jacky Mathijssen will be their new head coach for the upcoming season. Coach Cedomir Janevski is offered a position as his assistant but is still considering the offer.
April 28 - As both Club Brugge and Charleroi are still in the running for the fifth place and thus also possibly a ticket for European football next season, chairman Abbas Bayat decides to fire coach Jacky Mathijssen. Later that day the supporters chant Mathijssen's name during the match between Charleroi and Lokeren to express their unhappiness with Bayat's decision. Philippe Van de Walle is the caretaker for the four remaining matches of the season.