16-hydroxysteroid epimerase

16-hydroxysteroid epimerase
Identifiers
EC no.	5.1.99.2
CAS no.	37318-40-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a 16-hydroxysteroid epimerase (EC 5.1.99.2) is an enzyme that catalyzes the chemical reaction

16alpha-hydroxysteroid ${\displaystyle \rightleftharpoons }$ 16beta-hydroxysteroid

Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.

References

• Dahm K, Lindlau M, Breuer H (1968). "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta. 159 (2): 377–89. doi:10.1016/0005-2744(68)90086-7. PMID 5657462.