(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
Identifiers
EC no.	4.1.3.35
CAS no.	71343-09-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) catalyzes the chemical reaction

(1-hydroxycyclohexan-1-yl)acetyl-CoA ${\displaystyle \rightleftharpoons }$ acetyl-CoA + cyclohexanone

Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.

References

• Ougham HJ, Trudgill PW (June 1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". Journal of Bacteriology. 150 (3): 1172–82. PMC 216338. PMID 7076617.