TRAPPC4

TRAPPC4
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 2J3T, 2JSN, 2ZMV
Identifikatori
Aliasi	TRAPPC4
Vanjski ID-jevi	OMIM: 610971 MGI: 1926211 HomoloGene: 105453 GeneCards: TRAPPC4
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek)[1] Bend 11q23.3 Početak 119,018,763 bp[1] Kraj 119,025,454 bp[1]
Lokacija gena (miš) Hrom. Hromosom 9 (miš)[2] Bend 9|9 A5.2 Početak 44,314,995 bp[2] Kraj 44,318,897 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citosol • Golđijev aparat • Sinapsna vezikula • sinapsa • dendrit • Endoplazmatski retikulum • Golgi stack • Golđijeva membrana • TRAPP complex Biološki proces • dendrite development • COPII vesicle coating • vesicle-mediated transport • endoplasmic reticulum to Golgi vesicle-mediated transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	51399	60409
Ensembl	ENSG00000280495 ENSG00000196655	ENSMUSG00000032112
UniProt	Q9Y296	Q9ES56
RefSeq (mRNK)	NM_016146 NM_001318486 NM_001318488 NM_001318489 NM_001318490 NM_001318492 NM_001318494	NM_021789
RefSeq (bjelančevina)	NP_001305415 NP_001305417 NP_001305418 NP_001305419 NP_001305421 NP_001305423 NP_057230	NP_068561
Lokacija (UCSC)	Chr 11: 119.02 – 119.03 Mb	Chr 9: 44.31 – 44.32 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Podjedinica 4 čestica prometnog proteinskog kompleksa je protein koji je kod ljudi kodiran genom TRAPPC4.^[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 219 aminokiselina, а molekulska težina 24.340 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAIFSVYVVN		KAGGLIYQLD		SYAPRAEAEK		TFSYPLDLLL		KLHDERVLVA
FGQRDGIRVG		HAVLAINGMD		VNGRYTADGK		EVLEYLGNPA		NYPVSIRFGR
PRLTSNEKLM		LASMFHSLFA		IGSQLSPEQG		SSGIEMLETD		TFKLHCYQTL
TGIKFVVLAD		PRQAGIDSLL		RKIYEIYSDF		ALKNPFYSLE		MPIRCELFDQ
NLKLALEVAE		KAGTFGPGS

Reference

1. ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032112 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
6. "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".
7. "UniProt, Q9Y296". Pristupljeno 28. 8. 2021.

Dopunska literatura

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

Vanjski linkovi