NOL9

NOL9
Identifikatori
Aliasi	NOL9
Vanjski ID-jevi	MGI: 1921285 HomoloGene: 32589 GeneCards: NOL9
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek)[1] Bend 1p36.31 Početak 6,521,347 bp[1] Kraj 6,554,513 bp[1]
Lokacija gena (miš) Hrom. Hromosom 4 (miš)[2] Bend 4|4 E2 Početak 152,123,778 bp[2] Kraj 152,145,951 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • aktivnost sa transferazom • nucleotide binding • polynucleotide 5'-hydroxyl-kinase activity • GO:0001948, GO:0016582 vezivanje za proteine • ATP binding • vezivanje sa RNK • kinase activity Ćelijska komponenta • membrana • jedro • nukleoplazma • Jedarce • intermediate filament cytoskeleton Biološki proces • cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) • maturation of 5.8S rRNA • Fosforilacija • rRNA processing Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	79707	74035
Ensembl	ENSG00000162408	ENSMUSG00000028948
UniProt	Q5SY16	Q3TZX8
RefSeq (mRNK)	NM_024654	NM_001159599 NM_028727 NM_001378856
RefSeq (bjelančevina)	NP_078930	NP_001153071 NP_083003 NP_001365785
Lokacija (UCSC)	Chr 1: 6.52 – 6.55 Mb	Chr 4: 152.12 – 152.15 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Jedarcetov protein 9 jest protein koji je kod ljudi kodiran genom NOL9 sa hromosoma 1.^[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 702 aminokiseline, a molekulska težina 79.323 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MADSGLLLKR		GSCRSTWLRV		RKARPQLILS		RRPRRRLGSL		RWCGRRRLRW
RLLQAQASGV		DWREGARQVS		RAAAARRPNT		ATPSPIPSPT		PASEPESEPE
LESASSCHRP		LLIPPVRPVG		PGRALLLLPV		EQGFTFSGIC		RVTCLYGQVQ
VFGFTISQGQ		PAQDIFSVYT		HSCLSIHALH		YSQPEKSKKE		LKREARNLLK
SHLNLDDRRW		SMQNFSPQCS		IVLLEHLKTA		TVNFITSYPG		SSYIFVQESP
TPQIKPEYLA		LRSVGIRREK		KRKGLQLTES		TLSALEELVN		VSCEEVDGCP
VILVCGSQDV		GKSTFNRYLI		NHLLNSLPCV		DYLECDLGQT		EFTPPGCISL
LNITEPVLGP		PFTHLRTPQK		MVYYGKPSCK		NNYENYIDIV		KYVFSAYKRE
SPLIVNTMGW		VSDQGLLLLI		DLIRLLSPSH		VVQFRSDHSK		YMPDLTPQYV
DDMDGLYTKS		KTKMRNRRFR		LAAFADALEF		ADEEKESPVE		FTGHKLIGVY
TDFAFRITPR		NRESHNKILR		DLSILSYLSQ		LQPPMPKPLS		PLHSLTPYQV
PFNAVALRIT		HSDVAPTHIL		YAVNASWVGL		CKIQDDVRGY		TNGPILLAQT
PICDCLGFGI		CRGIDMEKRL		YHILTPVPPE		ELRTVNCLLV		GAIAIPHCVL
KCQRGIEGTV		PYVTTDYNFK		LPGASEKIGA		REPEEAHKEK		PYRRPKFCRK
MK

Reference

1. GRCh38: Ensembl release 89: ENSG00000162408 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028948 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. "Entrez Gene: NOL9 nucleolar protein 9".
7. "UniProt, Q5SY16" (jezik: eng.). Pristupljeno 3. 12. 2021.

Dopunska literatura

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Mol. Vis. 8: 205–20. PMID 12107410.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.