INTS9

INTS9
Identifikatori
AliasiINTS9
Vanjski ID-jeviOMIM: 611352 MGI: 1098533 HomoloGene: 10096 GeneCards: INTS9
Lokacija gena (čovjek)
Hromosom 8 (čovjek)
Hrom.Hromosom 8 (čovjek)[1]
Hromosom 8 (čovjek)
Genomska lokacija za INTS9
Genomska lokacija za INTS9
Bend8p21.1Početak28,767,661 bp[1]
Kraj28,890,242 bp[1]
Lokacija gena (miš)
Hromosom 14 (miš)
Hrom.Hromosom 14 (miš)[2]
Hromosom 14 (miš)
Genomska lokacija za INTS9
Genomska lokacija za INTS9
Bend14 D1|14 33.81 cMPočetak65,187,494 bp[2]
Kraj65,277,284 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta integrator complex
nukleoplazma
citosol
jedro
Biološki proces snRNA processing
snRNA transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001145159
NM_001172562
NM_018250
NM_001363038

NM_001253731
NM_153414

RefSeq (bjelančevina)

NP_001138631
NP_001166033
NP_060720
NP_001349967

NP_001240660
NP_700463

Lokacija (UCSC)Chr 8: 28.77 – 28.89 MbChr 14: 65.19 – 65.28 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Podjedinica 9 integratorskog kompleksa je protein koji je kod ljudi kodiran genom INTS9.[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 658 aminokiselina, а molekulska težina 73.814 Da.[7]

1020304050
MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLS
NLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVIL
ISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKA
QSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYS
QKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPM
DQASLKNSDVLVLTGLTQIPTANPDGMVGEFCSNLALTVRNGGNVLVPCY
PSGVIYDLLECLYQYIDSAGLSSVPLYFISPVANSSLEFSQIFAEWLCHN
KQSKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSL
RFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDT
RLNFIQVSKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYR
RAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNK
HLLQPPPRPAQPTSGKKRKRVSDDVPDCKVLKPLLSGSIPVEQFVQTLEK
HGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDL
VLKFLQKF

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000104299 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021975 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.
  6. ^ "Entrez Gene: RC74 integrator complex subunit 9".
  7. ^ "UniProt, Q9NV88" (jezik: engleski). Pristupljeno 19. 9. 2021.

Dopunska literatura

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