AHCTF1

AHCTF1
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 4I0O
Identifikatori
Aliasi	AHCTF1
Vanjski ID-jevi	OMIM: 610853 MGI: 1915033 HomoloGene: 9142 GeneCards: AHCTF1
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek)[1] Bend 1q44 Početak 246,839,098 bp[1] Kraj 246,931,948 bp[1]
Lokacija gena (miš) Hrom. Hromosom 1 (miš)[2] Bend 1 H4|1 83.62 cM Početak 179,572,459 bp[2] Kraj 179,631,245 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • vezivanje sa DNK • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • citoplazma • citosol • Jedarna membrana • nuclear periphery • nuclear matrix • jedrova pora • nukleoplazma • hromosom • nuclear pore outer ring • Hromatin • Egzosom • Primarno suženje • jedro • kinetohor • nuclear envelope Biološki proces • mRNA transport • nuclear pore complex assembly • GO:0009373 regulation of transcription, DNA-templated • Citokineza • Ćelijska dioba • protein transport • ćelijski ciklus • sister chromatid cohesion • GO:0015915 transport • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • regulation of cytokinesis Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	25909	226747
Ensembl	ENSG00000153207	ENSMUSG00000026491
UniProt	Q8WYP5	Q8CJF7
RefSeq (mRNK)	NM_015446 NM_001323342 NM_001323343 NM_175865	NM_026375
RefSeq (bjelančevina)	NP_001310271 NP_001310272 NP_056261	NP_080651
Lokacija (UCSC)	Chr 1: 246.84 – 246.93 Mb	Chr 1: 179.57 – 179.63 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Protein ELYS jest protein koji je kod ljudi kodiran genom AHCTF1 sa hromosoma 1.^[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 2.266 aminokiselina, a molekulska 252 498 težina Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MRDLRAQVTS		GLLPFPEVTL		QALGEDEITL		ESVLRGKFAA		GKNGLACLAC
GPQLEVVNSI		TGERLSAYRF		SGVNEQPPVV		LAVKEFSWQK		RTGLLIGLEE
TEGSVLCLYD		LGISKVVKAV		VLPGRVTAIE		PIINHGGASA		STQHLHPSLR
WLFGVAAVVT		DVGQILLVDL		CLDDLSCNQN		EVEASDLEVL		TGIPAEVPHI
RESVMRQGRH		LCFQLVSPTG		TAVSTLSYIS		RTNQLAVGFS		DGYLALWNMK
SMKREYYIQL		ESGQVPVYAV		TFQEPENDPR		NCCYLWAVQS		TQDSEGDVLS
LHLLQLAFGN		RKCLASGQIL		YEGLEYCEER		YTLDLTGGMF		PLRGQTSNTK
LLGCQSIEKF		RSHGDREEGV		NEALSPDTSV		SVFTWQVNIY		GQGKPSVYLG
LFDINRWYHA		QMPDSLRSGE		YLHNCSYFAL		WSLESVVSRT		SPHGILDILV
HERSLNRGVP		PSYPPPEQFF		NPSTYNFDAT		CLLNSGVVHL		TCTGFQKETL
TFLKKSGPSL		NELIPDGYNR		CLVAGLLSPR		FVDVQPSSLS		QEEQLEAILS
AAIQTSSLGL		LTGYIRRWIT		EEQPNSATNL		RFVLEWTWNK		VVLTKEEFDR
LCVPLFDGSC		HFMDPQTIQS		IQQCYLLLSN		LNIVLSCFAS		EAREITERGL
IDLSNKFVVS		HLICQYAQVV		LWFSHSGLLP		EGIDDSVQLS		RLCYNYPVIQ
NYYTSRRQKF		ERLSRGKWNP		DCLMIDGLVS		QLGERIEKLW		KRDEGGTGKY
PPASLHAVLD		MYLLDGVTEA		AKHSITIYLL		LDIMYSFPNK		TDTPIESFPT
VFAISWGQVK		LIQGFWLIDH		NDYESGLDLL		FHPATAKPLS		WQHSKIIQAF
MSQGEHRQAL		RYIQTMKPTV		SSGNDVILHL		TVLLFNRCMV		EAWNFLRQHC
NRLNIEELLK		HMYEVCQEMG		LMEDLLKLPF		TDTEQECLVK		FLQSSASVQN
HEFLLVHHLQ		RANYVPALKL		NQTLKINVMN		DRDPRLRERS		LARNSILDQY
GKILPRVHRK		LAIERAKPYH		LSTSSVFRLV		SRPKPLSAVP		KQVVTGTVLT
RSVFINNVLS		KIGEVWASKE		PINSTTPFNS		SKIEEPSPIV		YSLPAPELPE
AFFGTPISKA		SQKISRLLDL		VVQPVPRPSQ		CSEFIQQSSM		KSPLYLVSRS
LPSSSQLKGS		PQAISRASEL		HLLETPLVVK		KAKSLAMSVT		TSGFSEFTPQ
SILRSTLRST		PLASPSPSPG		RSPQRLKETR		ISFVEEDVHP		KWIPGAADDS
KLEVFTTPKK		CAVPVETEWL		KSKDRTTSFF		LNSPEKEHQE		MDEGSQSLEK
LDVSKGNSSV		SITSDETTLE		YQDAPSPEDL		EETVFTASKP		KSSSTALTTN
VTEQTEKDGD		KDVFASEVTP		SDLQKQMGNL		EDAETKDLLV		AAEAFSELNH
LSPVQGTEAS		LCAPSVYEGK		IFTQKSKVPV		LDEGLTSVET		YTPAIRANDN
KSMADVLGDG		GNSSLTISEG		PIVSERRLNQ		EVALNLKEDH		EVEVGVLKES
VDLPEEKLPI		SDSPPDTQEI		HVIEQEKLEA		QDSGEEARNL		SFNELYPSGT
LKLQYNFDTI		DQQFCDLADN		KDTAECDIAE		VDGELFVAQS		NFTLILEGEE
GEVEPGDFAS		SDVLPKAANT		ATEEKLVCSG		ENDNHGQIAN		LPSAVTSDQK
SQKVDTLPYV		PEPIKVAIAE		NLLDVIKDTR		SKEITSDTME		QSIHETIPLV
SQNIMCPTKL		VKSAFKTAQE		TSTMTMNVSQ		VDDVVSSKTR		TRGQRIQNVN
VKSAQQEASA		DVATPKMPGQ		SVRKKTRKAK		EISEASENIY		SDVRGLSQNQ
QIPQNSVTPR		RGRRKKEVNQ		DILENTSSVE		QELQITTGRE		SKRLKSSQLL
EPAVEETTKK		EVKVSSVTKR		TPRRIKRSVE		NQESVEIIND		LKVSTVTSPS
RMIRKLRSTN		LDASENTGNK		QDDKSSDKQL		RIKHVRRVRG		REVSPSDVRE
DSNLESSQLT		VQAEFDMSAI		PRKRGRPRKI		NPSEDVGSKA		VKEERSPKKK
EAPSIRRRST		RNTPAKSENV		DVGKPALGKS		ILVPNEELSM		VMSSKKKLTK
KTESQSQKRS		LHSVSEERTD		EMTHKETNEQ		EERLLATASF		TKSSRSSRTR
SSKAILLPDL		SEPNNEPLFS		PASEVPRKAK		AKKIEVPAQL		KELVSDLSSQ
FVISPPALRS		RQKNTSNKNK		LEDELKDDAQ		SVETLGKPKA		KRIRTSKTKQ
ASKNTEKESA		WSPPPIEIRL		ISPLASPADG		VKSKPRKTTE		VTGTGLGRNR
KKLSSYPKQI		LRRKML

Također pogledajte

• AT-kuka

Reference

1. GRCh38: Ensembl release 89: ENSG00000153207 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026491 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839.
6. "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".
7. "UniProt, Q8WYP5" (jezik: en.). Pristupljeno 7. 12. 2021.

Vanjski linkovi

• Lokacija ljudskog genoma AHCTF1 i stranica sa detaljima o genu AHCTF1 u UCSC Genome Browseru.

Dopunska literatura

• Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.