Terbequinil

Terbequinil

Clinical data
ATC code	none
Identifiers
IUPAC name 1-(methoxymethyl)-4-oxo-N-propylquinoline-3-carboxamide
CAS Number	113079-82-6^N
PubChem CID	65916
ChemSpider	59325^Y
UNII	0DH9WUS03O
CompTox Dashboard (EPA)	DTXSID50150281
Chemical and physical data
Formula	C15H18N2O3
Molar mass	274.320 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCCNC(=O)C1=CN(C2=CC=CC=C2C1=O)COC
InChI InChI=1S/C15H18N2O3/c1-3-8-16-15(19)12-9-17(10-20-2)13-7-5-4-6-11(13)14(12)18/h4-7,9H,3,8,10H2,1-2H3,(H,16,19)^Y Key:RIPDGZHPNKQLDC-UHFFFAOYSA-N^Y
^NY (what is this?)  (verify)

Terbequinil (SR-25776) is a stimulant and nootropic drug which acts as a partial inverse agonist at benzodiazepine sites on the GABA_A receptor. In human trials it was found to partially reverse the sedative and amnestic effects of the hypnotic drug triazolam with only slight effects when administered by itself.^[1]

See also

• GABA_A receptor negative allosteric modulator
• GABA_A receptor § Ligands

References

1. Warot D, Danjou P, Douillet P, Keane P, Puech AJ (1994). "Cognitive impairments induced by triazolam in healthy volunteers: antagonism by a partial inverse agonist of benzodiazepine receptor". Therapie. 49 (1): 23–6. PMID 8091361.