In 1981, Al-Amoudi was among the first doctors to graduate from the medical college in King Abdulaziz University.[2]
In April 2006, she diagnosed herself with breast cancer, for which she underwent chemotherapy.[2] She was the first Saudi woman to write publicly about her experience of the disease, which she did in a series of articles in a weekly column in the Al Madinah newspaper.[3] She also appeared on a daily TV show.[2]
In 2010, she was ranked fifth on the Power 100 list, which is Arabian Business's annual listing of the world's most influential Arabs.[2] Al-Amoudi was also later ranked by Arabian Business, as 37th in 2015 and 66th in 2016 of the "100 Most Powerful Arab Women 2016 - Healthcare & Science".[6]
Since 2012, the year she completed her cancer treatment, she has been head of the Sheikh Mohammed Hussein Al-Amoudi Center of Excellence in breast cancer and scientific chair for breast cancer at KAU, Jeddah Saudi Arabia, and is GE Healthcare's #GetFit Ambassador.[1]
Al-Mahoudi is CEO of Sheikh Mohammed Hussien Al-Amoudi Center of Excellence in Breast Cancer, is the Scientific breast cancer chair, a member of the BHGI steering committee, and an associate professor and consultant obstetrician gynecologist, at King Abdulaziz University, Jeddah, Saudi Arabia.[citation needed]