Riga–Fede disease

Riga–Fede disease
Riga-Fede disease on the lower lip.

Riga–Fede disease (RFD) is a rare and benign mucosal condition,^[1] characterized by a tongue ulcer that is frequently brought on by traumatizing injuries sustained from repeatedly moving the tongue back and forth over the mandibular anterior incisors.^[2]

Signs and symptoms

Clinically, it typically manifests as a tongue-localized ulcer (60 percent of lesions), though it can also affect the lip, palate, gingiva, vestibular mucosa, and floor of the mouth. RFD may not cause any symptoms or may occasionally be accompanied by pain.^[3]

Causes

RFD is most frequently linked to the emergence of the natal-neonatal teeth in newborns^[4] or the primary lower incisor in older infants.^[5]

Diagnosis

Histopathologically speaking, RFD is characterized by mucosal areas that are ulcerated, granulation tissue present, and a mixed inflammatory infiltrate that is abundant in mast cells, macrophages, lymphocytes, and eosinophils.^[6]

Treatment

The lesion can be removed, the sharp incisal edges can be smoothed, or the tooth's sharp edges can be rounded with composite increments. The latter is where mild to moderate ulceration can occur. Teeth extraction may be helpful if the ulceration is large and preventing the patient from eating.^[7]

References

1. Ceyhan, A. M.; Yildirim, M.; Basak, P. Y.; Akkaya, V. B.; Ayata, A. (2009). "Traumatic lingual ulcer in a child: Riga-Fede disease". Clinical and Experimental Dermatology. 34 (2). Oxford University Press (OUP): 186–188. doi:10.1111/j.1365-2230.2008.02796.x. ISSN 0307-6938. PMID 19187299. S2CID 25772663.
2. Baroni, Adone; Capristo, Carlo; Rossiello, Luigi; Faccenda, Franco; Satriano, Rocco Alfredo (July 19, 2006). "Lingual traumatic ulceration (Riga–Fede disease)". International Journal of Dermatology. 45 (9). Wiley: 1096–1097. doi:10.1111/j.1365-4632.2004.02554.x. ISSN 0011-9059. PMID 16961520. S2CID 42438172.
3. Joseph, Bobby K.; BairavaSundaram, Devipriya (January 7, 2010). "Oral traumatic granuloma: report of a case and review of literature". Dental Traumatology. 26 (1). Wiley: 94–97. doi:10.1111/j.1600-9657.2009.00816.x. ISSN 1600-4469. PMID 20089067.
4. Hegde, RJ (2005). "Sublingual traumatic ulceration due to neonatal teeth (Riga-Fede disease)". Journal of Indian Society of Pedodontics and Preventive Dentistry. 23 (1). Medknow: 51–52. doi:10.4103/0970-4388.16031. ISSN 0970-4388. PMID 15858311.
5. Slayton, R L (2000). "Treatment alternatives for sublingual traumatic ulceration (Riga-Fede disease)" (PDF). Pediatric Dentistry. 22 (5): 413–414. PMID 11048312. Retrieved 21 January 2024.
6. Iandolo, A.; Amato, A.; Sangiovanni, G.; Argentino, S.; Pisano, M. (2021). "Riga-Fede disease: A systematic review and report of two cases". European Journal of Paediatric Dentistry. 22 (4). ARIESDUE SRL: 323–331. doi:10.23804/ejpd.2021.22.04.11. PMID 35034468.
7. Jariwala, D.; Graham, R. M.; Lewis, T. (2008). "Riga-Fede disease". British Dental Journal. 204 (4). Springer Science and Business Media LLC: 171. doi:10.1038/bdj.2008.113. ISSN 0007-0610.

Further reading

• Costacurta, M.; Maturo, P.; Docimo, R. (2012). "Riga-Fede disease and neonatal teeth". Oral & Implantology. 5 (1). CIC Edizioni Internazionali: 26–30. PMC 3533976. PMID 23285403.
• Volpato, Luiz Evaristo Ricci; Simões, Cintia Aparecida Damo; Simões, Flávio; Nespolo, Priscila Alves; Borges, Álvaro Henrique (2015). "Riga-Fede Disease Associated with Natal Teeth: Two Different Approaches in the Same Case". Case Reports in Dentistry. 2015. Hindawi Limited: 1–4. doi:10.1155/2015/234961. ISSN 2090-6447. PMC 4569785. PMID 26421196.

External links

• Whonamedit?
• DermNet