Prifinium bromide

Prifinium bromide

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	A03AB18 (WHO)
Identifiers
IUPAC name 3-(Diphenylmethylene)-1,1-diethyl-2-methylpyrrolidinium bromide
CAS Number	4630-95-9^N
PubChem CID	20749
ChemSpider	19537^Y
UNII	3B7O9ZC520
ChEMBL	ChEMBL1213353^Y
CompTox Dashboard (EPA)	DTXSID3023508
ECHA InfoCard	100.022.774
Chemical and physical data
Formula	C22H28BrN
Molar mass	386.377 g·mol^−1
InChI InChI=1S/C22H28N.BrH/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20;/h6-15,18H,4-5,16-17H2,1-3H3;1H/q+1;/p-1^Y Key:UCGJZJXOPSNTGZ-UHFFFAOYSA-M^Y
^NY (what is this?)  (verify)

Prifinium bromide is a pharmaceutical drug used primarily in the treatment of irritable bowel syndrome due to its action as an anticholinergic.^[1]

Prifinium bromide's mechanism of action is believed to be due to its activity as an antispasmodic agent.^[2]

Prifinium bromide is an antimuscarinic.^[3]

References

1. Piai, Guido (1975). "[Prifinium bromide in the treatment of the irritable colon syndrome]". Gastroenterology. 77 (3): 500–502. PMID 37142.
2. Silber W (1979). "[Prifinium bromide-a new antispasmodic.]". South African Medical Journal. 56 (24): 1033–1034. PMID 45057.
3. Magalini M, Monica F (June 1995). "[Use of prifinium bromide in endoscopic premedication. A double-blind controlled study vs hyoscine N-butylbromide]". Minerva Gastroenterologica e Dietologica. 41 (2): 197–202. PMID 7647144.