Cristofer was born Michael Procaccino in Trenton, New Jersey, the son of Mary and Joseph Procaccino.[2] He started his theatrical career as an actor, primarily on stage. He also started writing plays. He has also written numerous screenplays for film.
For eight years, he worked as artistic advisor and finally co-artistic director of River Arts Repertory in Woodstock, New York, a company which produced plays by writers such as Richard Nelson, Mac Wellman, and Eric Overmeyer, including the American premiere of Edward Albee's Three Tall Women, a production that later moved to Off-Broadway.
Also at River Arts, he wrote stage adaptations of the films Love Me or Leave Me and Casablanca. He directed Joanne Woodward in his adaptation of Henrik Ibsen's Ghosts. His most recent work for the theater, The Whore and Mr. Moore, premiered at Dorset Theatre Festival's 2012 summer season. He collaborated with trumpeter Terence Blanchard, writing the libretto for Champion, a boxing opera in jazz music based on the life of prize fighter Emile Griffith. It premiered in June 2013 at Opera Theater of St. Louis. His work Execution of the Caregiver is based on the true story of a woman in South Carolina who killed her mother, fiancé and several people for whom she purportedly was caring.[4]
In 2010, Cristofer was a cast member on Rubicon, in which he played Truxton Spangler.[citation needed] In 2012, he played Jerry Rand on Smash.[5]
In 2013–2014, he played millionaire witch-hunter Harrison Renard in American Horror Story: Coven. In 2015, Cristofer made guest appearances in four episodes of season one of Mr. Robot as Phillip Price, the shadowy CEO of the sinister E Corp, and he became a cast member in season two, three, and four.[citation needed]