Miyano was born in Saitama Prefecture.[1][2] He joined Himawari Theatre Group under the influence of his older brother Shota, though he did not attend the class often. After entering high school and due to the uncertainty he felt toward the future, Miyano skipped singing and dance lessons. While taking music lessons, he discovered his musical style through the encounter with music produced by singers like CHEMISTRY and Exile.[citation needed] In 2008, Miyano announced he was married and his wife was pregnant. They have a son.[3] On December 21, 2023, Miyano released a statement on his official website announcing his divorce.[4]
Miyano made his singing debut, releasing his first single "Kuon" (久遠, Eternity) for King Records label on May 28, 2007.[11] "Kuon" debuted at #47 on the Oricon charts which became the finale theme song in the anime series Kōtetsu Sangokushi.[12] He released a duet with Romi Park, entitled "Fight", which debuted at # 73 on the Oricon chart on June 13, 2007.[13] Miyano reprised his role for Kingdom Hearts Re:Chain of Memories.[14][15] Miyano voiced Setsuna F. Seiei, the main character in Mobile Suit Gundam 00. He won his first award, "Best Voice Actor", at the 2008 Tokyo International Anime Fair for his portrayal of Light Yagami and Setsuna F. Seiei.[16]
On June 4, 2008, he released his second single, "Discovery", used as which became the intro song for the video game Fushigi Yūgi: Suzaku Ibun.[17] The song debuted at # 24 on the Oricon chart.[18] In August, Miyano released the character single "Soup/Hakosora", entitled "Mamoru Miyano Comes Across Setsuna F. Seiei" (宮野真守 come across 刹那・F・セイエイ), debuting at # 18.[19] In December he released his third single, "...Kimi e" (...君へ, ...To You), which also debuted at # 18.[20] That year, Miyano reprised the role of Setsuna F. Seiei for the second season of Mobile Suit Gundam 00 for which he won his first Seiyuu Award and another for the role of Hakugen Rikuson in Kōtetsu Sangokushi.[21] He has also voiced Zero Kiryu and Ichiru Kiryu both from the series Vampire Knight and Vampire Knight Guilty, as well as Death The Kid in the anime Soul Eater. He voiced Tamaki Suoh in the anime version of Ouran High School Host Club, Rintaro Okabe in Steins Gate, Ling Yao in Fullmetal Alchemist: Brotherhood, Oda Nobunaga in Nobunaga the Fool, Rin Matsuoka in Free!, and Osamu Dazai in Bungou Stray Dogs. Miyano appeared on-camera, including a guest spot on the 2008 drama The Quiz Show.[citation needed]
In 2010, Miyano released his second album, Wonder. The album charted at number 20 on the Oricon Weekly Albums chart. Following the album's release, Miyano went on his second tour, Mamoru Miyano Live Tour 2010: Wondering. He voiced Dent in the popular Pokémon anime series. He starred in Daisuke Namikawa's live action film Wonderful World.[23]
Miyano participated in the 2011 theatrical play Ultraman Premier in Tokyo, where he played Shin Moroboshi, the human guise of Ultraman Zero.[24] In April 2012, Miyano released his third album, Fantasista. The album charted at number 4 on the Oricon Weekly Albums chart.[25] Miyano made his first appearance on NHK's music variety show Music Japan.[citation needed] In 2013, he became the first male voice actor to perform solo at Nippon Budokan arena.[26]
In April 2014, he released the DVD for his 5th live tour, "~TRAVELING!~". The following month he began his 6th live tour ~Wakening!~ where he traveled around Japan. The DVD was released January 28, 2015.[27]
In 2015, he became the first male voice actor with number 1 single on Oricon daily chart.[28]
On July 10, 2016, he was one of the performers to appear in "Ultraman Day", a festival that celebrated the 50th anniversary of Ultra Series.[29][30]
On February 11 and 12, 2017, he held his first solo foreign concert in Taiwan.[31] In June 2017, he became the first male voice actor to top weekly Blu-ray chart.[32]