The constituency was created for the 1885 general election, and abolished for the February 1974 general election. In every postwar election until its abolition, it was the safest Conservative seat (excluding Northern Irish constituencies) in the country.
Prior to 1885, the area was originally part of the Chelsea constituency. Following the Redistribution of Seats Act 1885, the new Kensington South seat was a single-member constituency consisting of all of the parliamentary borough of Kensington south of the Uxbridge Road.
In the 1950 redistribution, Brompton ward was transferred to the Chelsea constituency. The constituency was thus now defined as consisting of the Royal Borough of Kensington wards of Earl's Court, Holland, Queen's Gate, and Redcliffe. It then remained unchanged until its abolition in 1974.
In the 1974 redistribution, this constituency disappeared. Earl's Court and Redcliffe wards became part of the redrawn Chelsea constituency, while Holland and Queen's Gate wards became part of the new Kensington constituency.