Arndt won the national individual pursuit championship four times and Olympic bronze in the same competition. But a viral infection during the 2000 Summer Olympics – causing a disappointing outcome – marked the turning in her career. In two years, she finished third in the Grande Boucle (sometimes referred to as the "women's Tour de France)" in 2003, won the Tour de l'Aude twice (2002 and 2003),[2] and added a silver medal in the road time trial at the 2003 world championship in Hamilton, Ontario.[3]
At the 2004 Summer Olympics in Athens, Greece she won silver in the road race,[2] and, two weeks later, became world road champion at Verona, Italy. She finished first in the UCI world ranking.
In 2005, she won the national road championship for the sixth time.[4]
Arndt was appointed as a member of the inaugural UCI Athletes' Commission in 2011.[5]
Arndt has lived in Leipzig since 1996, with her partner, fellow cyclist Petra Rossner.[7][8] The couple became Gay Games ambassadors in 2005.[9][10] In 2012, after the World Cup, she was in a relationship with Australian lawyer, and former cyclist Anna Wilson, and moved to Melbourne.[8]