Ethyltrifluoromethylaminoindane

Ethyltrifluoromethylaminoindane

Identifiers
IUPAC name N-ethyl-5-(trifluoromethyl)-2,3-dihydro-1H-inden-2-amine
CAS Number	205652-94-4^N
PubChem CID	10331389
ChemSpider	8506849^N
UNII	SU92GOM6PI
CompTox Dashboard (EPA)	DTXSID701028480
Chemical and physical data
Formula	C12H14F3N
Molar mass	229.246 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCNC1CC2=C(C1)C=C(C=C2)C(F)(F)F
InChI InChI=1S/C12H14F3N/c1-2-16-11-6-8-3-4-10(12(13,14)15)5-9(8)7-11/h3-5,11,16H,2,6-7H2,1H3^N Key:PHTXVQQRWJXYPP-UHFFFAOYSA-N^N
^NY (what is this?)  (verify)

N-Ethyl-5-trifluoromethyl-2-aminoindane (ETAI) is a drug of the 2-aminoindane group with putative entactogenic effects. It functions as a selective serotonin releasing agent (SSRA). ETAI is the aminoindane analogue of fenfluramine and is approximately 50% as neurotoxic in comparison.^[1]

References

1. Cozzi NV, Frescas S, Marona-Lewicka D, Huang X, Nichols DE (March 1998). "Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential". Pharmacology Biochemistry and Behavior. 59 (3): 709–15. doi:10.1016/S0091-3057(97)00557-1. PMID 9512076. S2CID 41048219.