Aprilia rejoined the MotoGP class in 2012, taking advantage of the newly introduced Claiming Rule Team category that encouraged independent teams with lower budgets to use bikes from manufacturers not officially involved in MotoGP. Aprilia supplied RSV4 SBK-derived bikes under the ART (Aprilia Racing Technology) name to Aspar Team, Paul Bird Motorsport and Speed Master teams. In both the 2012 and 2013 seasons Aprilia's ART machinery stood out as the best CRT bikes.[citation needed]
In 2015, Aprilia partnered with Gresini Racing as a factory-supported independent team. The team competed as the Aprilia Racing Team Gresini with an all-new 1000cc V4-engined RS-GP.[citation needed]
In 2022, Aprilia entered the series as an official factory team for the first time since 2004.[1] Their previously supported Gresini Racing team returned to a fully-independent team using Ducati bikes. Aprilia's factory team is named Aprilia Racing.