3β-Hydroxytibolone

3β-Hydroxytibolone
Clinical data
Other namesORG-30126; 7α-Methyl-17α-ethynylestr-5(10)-ene-3β,17β-diol
Identifiers
  • (3S,7R,8R,9S,13S,14S,17R)-17-ethynyl-7,13-dimethyl-2,3,4,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H30O2
Molar mass314.469 g·mol−1
3D model (JSmol)
  • C[C@@H]1CC2=C(CC[C@@H](C2)O)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O
  • InChI=1S/C21H30O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,15,17-19,22-23H,5-12H2,2-3H3/t13-,15+,17-,18+,19-,20+,21+/m1/s1
  • Key:YLEUWNOTNJZCBN-XAAPQAIWSA-N

3β-Hydroxytibolone (developmental code name ORG-30126) is a synthetic steroidal estrogen which was never marketed.[1][2] Along with 3α-hydroxytibolone and δ4-tibolone, it is a major active metabolite of tibolone, and 3α-hydroxytibolone and 3β-hydroxytibolone are thought to be responsible for the estrogenic activity of tibolone.[1][2]

References

  1. ^ a b Kuhl, H (2005). "Pharmacology of estrogens and progestogens: influence of different routes of administration". Climacteric. 8 (sup1): 3–63. doi:10.1080/13697130500148875. ISSN 1369-7137. PMID 16112947. S2CID 24616324.
  2. ^ a b Escande A, Servant N, Rabenoelina F, Auzou G, Kloosterboer H, Cavaillès V, Balaguer P, Maudelonde T (2009). "Regulation of activities of steroid hormone receptors by tibolone and its primary metabolites". J. Steroid Biochem. Mol. Biol. 116 (1–2): 8–14. doi:10.1016/j.jsbmb.2009.03.008. PMID 19464167. S2CID 18346113.



Stub icon

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.

Stub icon

This article about a steroid is a stub. You can help Wikipedia by expanding it.

Read other articles:

بيترو (اسم)

هذه المقالة يتيمة إذ تصل إليها مقالات أخرى قليلة جدًا. فضلًا، ساعد بإضافة وصلة إليها في مقالات متعلقة بها. (يوليو 2021) بترو (باليونانية: Πέτρου)‏ هو اسم عائلة يوناني.[1] الأشخاص الذين يحملون هذا اللقب هم: ماريا بيترو (1953-2012) - عالمة كمبيوتر بريطانية يونانية المولد. كوستاس بي...

 

Imagination (Deni Hines album)

1996 studio album by Deni HinesImaginationStudio album by Deni HinesReleased20 May 1996RecordedRed Bus Studios, 1995-1996GenrePopLabelMushroom RecordsWarner Bros. RecordsProducerIan Green, Martyn WareDeni Hines chronology Imagination(1996) Remix Your Imagination(1997) Alternative cover1997 edition Imagination is the debut studio album by Australian singer songwriter, Deni Hines. At the ARIA Music Awards of 1996, Imagination was nominated for two awards - ARIA Award for Best Female Art...

 

Лікарка і полковник

«Лікарка і полковник»італ. La dottoressa ci sta col colonnello Лікарка і полковник (1980)Жанр італійська еротична комедіяРежисер Мікеле Массімо ТарантініСценарист Франческо МіліціяМікеле Массімо ТарантініУ головних ролях Надя КассініОператор Mario VulpianidХудожник Adriana BellonedКінокомпанія Dani...

Museum Suzhou

Halaman Utama Museum Suzhou Museum Suzhou (Hanzi: 蘇州博物館; Pinyin: Sūzhōu Bówùguǎn) adalah sebuah museum seni rupa Tionghoa, lukisan Tionghoa, kaligrafi Tionghoa, dan kerajinan tangan, yang terletak di Suzhou, Jiangsu, China. Biaya masuknya gratis. Museum Foklor Suzhou terletak di kuil leluhur keluarga Bei Referensi Pranala luar Wikimedia Commons memiliki media mengenai Suzhou Museum. Situs web resmi China Museums Diarsipkan 2018-08-05 di Wayback Machine. Suzhou Museum at...

 

Male and Female

1919 film by Cecil B. DeMille For other uses, see Male and Female (disambiguation). Male and FemaleStill of Gloria Swanson in the filmDirected byCecil B. DeMilleWritten byJeanie MacPhersonBased onThe Admirable Crichtonby J. M. BarrieProduced byCecil B. DeMilleJesse L. LaskyStarringGloria SwansonThomas MeighanCinematographyAlvin WyckoffEdited byAnne BauchensMusic bySydney Jill Lehman (1997 version)ProductioncompanyFamous Players–Lasky/ArtcraftDistributed byParamount PicturesRelease date Nove...

 

The Kuguars

Rock band The KuguarsBackground informationOriginBelgrade, Serbia, FR YugoslaviaGenresComedy rockYears active1997–2001LabelsMetropolis RecordsPast membersDragan JovanovićDejan MatićNikola ÐuričkoRade MarkovićBoris MilivojevićBogdan DiklićPapa NickTibor Tot The Kuguars (a transliterated pun for The Cougars) were a successful short-lived Serbian comedy rock band from Belgrade, mainly consisting of famous Serbian actors. Formed in 1997, the band released two albums featuring humorous so...

Marathon Man (film)

1976 film by John Schlesinger Marathon ManMovie poster by Bill GoldDirected byJohn SchlesingerScreenplay byWilliam GoldmanBased onMarathon Manby William GoldmanProduced by Robert Evans Sidney Beckerman Starring Dustin Hoffman Laurence Olivier Roy Scheider William Devane Marthe Keller CinematographyConrad HallEdited byJim ClarkMusic byMichael SmallProductioncompanyRobert Evans-Sidney Beckerman ProductionsDistributed byParamount PicturesRelease date October 8, 1976 (1976-10-08) R...

 

Vladimir Kazantsev (athlete)

Vladimir KazantsevPersonal informationBorn(1923-01-06)January 6, 1923Alekseyevka, Khvalynsky Uyezd, Saratov Governorate, RSFSR, Soviet UnionDiedNovember 22, 2007(2007-11-22) (aged 84)Moscow, RussiaHeight176 cm (5 ft 9 in)Weight66 kg (146 lb)SportSportAthleticsEvent(s)Steeplechase, 5000 m, 10,000 mClubDynamo MoscowAchievements and titlesPersonal best(s)3000 mS – 8:48.6 (1952)5000 m – 14:08.8 (1952)10,000 m – 30:20.0 (1950)[1] Medal record Representin...

 

Pyramid of Ahmose

Smooth-sided pyramid This article uses bare URLs, which are uninformative and vulnerable to link rot. Please consider converting them to full citations to ensure the article remains verifiable and maintains a consistent citation style. Several templates and tools are available to assist in formatting, such as reFill (documentation) and Citation bot (documentation). (August 2022) (Learn how and when to remove this template message) This article needs additional citations for verification. Plea...

Peluruhan alfa

Peluruhan alfa adalah salah satu bentuk peluruhan radioaktif di mana sebuah inti atom berat tidak stabil melepaskan sebuah partikel alfa dan meluruh menjadi inti yang lebih ringan dengan nomor massa empat lebih kecil dan nomor atom dua lebih kecil dari semula, menurut reaksi: Z A X → Z − 2 A − 4 X ′ + 2 4 He 2 + , {\displaystyle {}_{Z}^{A}{\hbox{X}}\;\to \;{}_{Z-2}^{A-4}{\hbox{X}}'\;+\;{}_{2}^{4}{\hbox{He}}^{2+},} di mana X dan X' menyatakan jenis inti yang berbeda...

 

Štadión MUDr. Ivana Chodáka

Football stadium in Dolný Kubín, Slovakia The topic of this article may not meet Wikipedia's notability guideline for sports and athletics. Please help to demonstrate the notability of the topic by citing reliable secondary sources that are independent of the topic and provide significant coverage of it beyond a mere trivial mention. If notability cannot be shown, the article is likely to be merged, redirected, or deleted.Find sources: Štadión MUDr. Ivana Chodáka – news&...

 

Imbros

Island in Turkey This article is about the island. For other uses, see Imbros (disambiguation). Gökçeada redirects here. For the district, see Gökçeada District. For the town, see Gökçeada (town). ImbrosNative name: GökçeadaİmrozSatellite view of Gökçeada in 2016ImbrosShow map of MarmaraImbrosShow map of TurkeyImbrosShow map of EuropeGeographyLocationAegean SeaCoordinates40°09′39″N 25°50′40″E / 40.16083°N 25.84444°E / 40.16083; 25.84444Area286.8&...

Supari (film)

2003 Indian action film SupariFilm posterDirected byPadam KumarScreenplay byPadam KumarAnuradha TiwariMushtaq ShiekhProduced byPadam KumarStarringUday ChopraRahul DevNandita DasPurab KohliNauheed CyrusiIrrfan KhanCinematographyR. VelrajEdited bySanjay VermaMusic byVishal–ShekharDistributed byYash Raj FilmsRelease date 20 June 2003 (2003-06-20) [1]Running time143 minutes[2]CountryIndiaLanguageHindiBudget₹ 4.25 crore[3]Box office₹ 2.65 crore[4 ...

 

Орехов, Виталий Владимирович

В Википедии есть статьи о других людях с фамилией Орехов. Для улучшения этой статьи желательно: Оформить статью по правилам.Исправить статью согласно стилистическим правилам Википедии.Добавить иллюстрации.После исправления проблемы исключите её из списка. Удалите шаб...

 

World Book Day

Annual event to promote reading, publishing, and copyright Copyright Day redirects here. Not to be confused with Public Domain Day. World Book DayUNESCO World Book and Copyright Day 2012 posterOfficial nameWorld Book and Copyright DayAlso calledWBDObserved byAll UN Member StatesTypeInternationalDate23 AprilNext time23 April 2024 (2024-04-23)Frequencyannual World Book Day, also known as World Book and Copyright Day or International Day of the Book, is an annual event organized b...

Big Wheel (tricycle)

Children's toy vehicle A child on a Big Wheel, Rogers Park, Chicago, 1973 Big Wheel is a brand of low-riding tricycles, made mostly of plastic, with a larger front wheel. Introduced by Louis Marx and Company in 1969 and manufactured in Girard, Pennsylvania, Big Wheel was a very popular toy in the 1970s in the United States, partly because of its low cost and partly because consumer groups said it was a safer alternative to the traditional tricycle or bicycle. The large front wheel also made i...

 

Gerardo Romano (actor)

«Gerardo Romano» redirige aquí. Para el pelotari Gerardo Gabriel Romano, véase Gerardo Romano (pelotari). Gerardo Romano Gerardo Romano en 2021.Información personalNombre de nacimiento Luis Gerardo RomanoNacimiento 6 de julio de 1946 (77 años)Buenos Aires,  ArgentinaNacionalidad ArgentinaReligión AteoFamiliaPareja Leonor BenedettoAndrea Bonelli (1988 - 1991)Hijos Lucio Romano Bonelli Rita RomanoEducaciónEducado en Universidad de Buenos Aires Información profesionalOcupació...

 

Fungsionalisme (hubungan internasional)

Teori hubungan internasional Realisme Realisme neoklasik Neorealisme (realisme struktural) Realisme klasik Realisme ofensif Realisme defensif Realisme liberal (Mazhab Inggris) Keunggulan relatif Keunggulan absolut Realisme strategis Liberalisme Idealisme Teori perdamaian demokratis Liberalisme republik Institusionalisme Neoliberalisme Liberalisme interdependensi Liberalisme sosiologis Liberalisme institusional Konstruktivisme Konstruktivisme modern Konstruktivisme pascamodern Konstruktivisme ...

Damiano Pippi

Italian volleyball player Damiano PippiPersonal informationFull nameDamiano PippiNationalityItalianBorn (1971-08-23) 23 August 1971 (age 52)Height194 cm (6 ft 4 in)Weight75 kg (165 lb) Medal record Men's volleyball Representing  Italy Olympic Games 2004 Athens Team competition World Cup 2003 Japan Team competition Damiano Pippi (born 23 August 1971 in Castiglione del Lago) is a former volleyball player from Italy who won the silver medal with the Italia...

 

عضلة ألوية وسطى

عضلة ألوية وسطى الاسم العلميmusculus gluteus medius العضلة الألوية الوسطى والعضلات القريبة منها. عضلة ألوية وسطى تفاصيل منشأ العضلة الوجه الألوي من عظم الحرقفة، تحت أجربة مدورية للعضلة الألوية المتوسطة مغرز العضلة مدور كبير من عظم فخذ الشريان المغذي شريان ألوي علوي الأعصاب عصب ألو...

 

Strategi Solo vs Squad di Free Fire: Cara Menang Mudah!