Source: Lega Pro (in Italian), Soccerway (in English) Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Goal difference; 5) Goals scored; 6) Lower goals against; 7) Wins; 8) Lower losses; 9) Away wins; 10) Lower home losses.[22] (C) Champions; (D) Disqualified; (O) Play-off winners; (P) Promoted; (R) Relegated Notes:
^ abNovara finished ahead of Piacenza on head-to-head points: Piacenza 3–3 Novara, Novara 2–0 Piacenza.
^ abcGiana Erminio and Pergolettese finished ahead of Carrarese on head-to-head points: Giana Erminio 7, Pergolettese 7, Carrarese 3. Giana Erminio finished ahead of Pergolettese on head-to-head points: Giana Erminio 2–0 Pergolettese, Pergolettese 0–0 Giana Erminio.
^ abSince Carrarese finished more than 8 points ahead of Lucchese, the relegation play-out was not played and Lucchese were originally relegated directly.
^ abSince Pro Sesto finished more than 8 points ahead of Pistoiese, the relegation play-out was not played and Pistoiese were originally relegated directly.
^ abPistoiese finished ahead of Lucchese on head-to-head goal difference: Pistoiese 2–0 Lucchese, Lucchese 1–0 Pistoiese.
^Livorno have 5 points deducted due to financial irregularities
Source: Lega Pro (in Italian), Soccerway (in English) Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Goal difference; 5) Goals scored; 6) Lower goals against; 7) Wins; 8) Lower losses; 9) Away wins; 10) Lower home losses.[24] (C) Champions; (D) Disqualified; (O) Play-off winners; (P) Promoted; (R) Relegated Notes:
^ abPerugia finished ahead of Padova on head-to-head goal difference: Perugia 3–0 Padova, Padova 1–0 Perugia.
^ abVirtus Verona qualified to the Promotion play-offs since Modena was the best fourth-placed team based on points per game: Modena 1.842, Bari 1.750, Pro Vercelli 1.657.
^Sambenedettese have 4 points deducted due to financial irregularities.[23]
^ abMantova finished ahead of Virtus Verona on head-to-head points: Virtus Verona 1–1 Mantova, Mantova 3–2 Virtus Verona.
^ abVis Pesaro finished ahead of Carpi on head-to-head points: Vis Pesaro 3–2 Carpi, Carpi 0–2 Vis Pesaro.
Source: Lega Pro (in Italian), Soccerway (in English) Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Goal difference; 5) Goals scored; 6) Lower goals against; 7) Wins; 8) Lower losses; 9) Away wins; 10) Lower home losses.[26] (C) Champions; (D) Disqualified; (O) Play-off winners; (P) Promoted; (R) Relegated Notes:
^ abCatanzaro finished ahead of Avellino on head-to-head goal difference: Avellino 1–3 Catanzaro, Catanzaro 0–1 Avellino.
^Catania have 2 points deducted due to financial irregularities.
^ abPotenza finished ahead of Turris on head-to-head points: Turris 0–2 Potenza, Potenza 2–1 Turris.
^ abSince Vibonese finished more than 8 points ahead of Cavese, the relegation play-out was not played and Cavese were relegated directly.
^Trapani had 1 point deducted for deserting home match against Casertana, then they were excluded from league after failing to attend a second consecutive match.[25]
Promotion play-offs
A total of 28 teams qualified for the promotion play-offs. The winner of the play-offs earns promotion to Serie B.[27]
First preliminary round
The fixtures pair the 5th vs 10th, 6th vs 9th and 7th vs 8th-placed teams. In the group with the best 4th-placed team, the 5th placed team advances automatically to the second preliminary round and the revised fixtures are 6th vs 11th, 7th vs 10th and 8th vs 9th. If teams are tied after regular time, the higher-placed team advances.
Matches were played on 9 May 2021. The Triestina vs Virtus Verona game, originally scheduled to be played on 9 May 2021, was delayed due to eight cases of COVID-19 infection involving the latter club.[28] Match was later played on 16 May 2021.[29]
The fixtures pair the 4th-placed team vs the worst-placed team and the best-placed team vs the 2nd best-placed team from the first preliminary round. The best 4th-placed team in regular season advances automatically to the first national round and their berth is transferred to the 5th-placed team of the same group. If teams are tied after regular time, the higher-placed team advances.
The three 3rd-placed teams, the best 4th-placed team and the best-placed team from the second preliminary round (Bari) are seeded and host the second leg. No away goal rule applies. If teams are tied on aggregate, the seeded team advances.
The draw for the first national round was held on 20 May 2021, 11:00 CEST (UTC+2). The first legs were played on 23 May 2021 and the second legs were played on 26 May 2021.
The three 2nd-placed teams and the best-placed team from the first national round (Südtirol) are seeded and host the second leg. No away goal rule applies. If teams are tied on aggregate, the seeded team advances.
The draw for the second national round was held on 27 May 2021, 11:00 CEST (UTC+2). The first legs were played on 30 May 2021 and the second legs were played on 2 June 2021.
No away goal rule applies. If teams are tied on aggregate, the winner is decided by extra-time and a penalty shootout if required.
The draw for Final Four was held on 27 May 2021, 11:00 CEST (UTC+2), after the second national round draw. The semi-finals legs were played on 6 and 9 June 2021 and the final legs were played on 13 and 17 June 2021.
A total of 6 teams qualified for the relegation play-outs. The fixtures pair the 16th vs 19th and 17th vs 18th-placed teams, with higher-placed team playing at home for second leg. No away goal rule applies. If teams are tied on aggregate, the lower-placed team is relegated to Serie D.[27]
The first legs were played on 15 May 2021 and the second legs were played on 22 May 2021. The Fano vs Imolese game was postponed due to a cluster of confirmed COVID-19 cases involving the former team.[30] Match was played on 22 May 2021, whilst the second leg was played on 29 May 2021.[31]