The 1880 United States House of Representatives elections in South Carolina were held on November 2, 1880, to elect five representatives Representatives for two-year terms from the state of South Carolina. All five incumbents were re-elected and the composition of the state delegation remained solely Democratic.
"Annual Report of the Secretary of State to the General Assembly of South Carolina." Reports and Resolutions of the General Assembly of the State of South Carolina at the Regular Session of 1880. Columbia, SC: James Woodrow, 1881, pp. 553–555.