脂肪乳

脂肪乳
脂肪乳 (Intralipid) 20%
臨床資料
商品名英语Drug nomenclatureIntralipid、Nutrilipid及其它
其他名稱脂肪乳化劑靜脈營養輸液、脂肪乳劑、脂肪乳劑療法、脂質急救療法
AHFS/Drugs.comFDA专业药物信息


脂肪乳,全名為脂肪乳化劑靜脈營養輸液,較有名的商品名為Intralipid,是一种靜脈注射脂類溶液[2]。传统上作為腸道外營養的一部分[2]。它们还用于治疗多种中毒症,包括局部麻醉药乙型交感神經阻斷劑鈣離子通道阻滯劑中毒有机磷酸酯中毒抗精神病药中毒[1] [2]

副作用通常很少,但包括可能过敏胰腺炎急性呼吸窘迫症候群[1]。若患有某些真菌感染,使用脂肪乳可能使治療更為複雜[2]。此外,它用於解毒的作用機轉並不清楚[1]

脂肪乳自1961年起於医疗上使用[2]。在1998年起用于解毒[3]。不同版本的製劑,成份来源不同[1]。常见来源包括大豆椰子油橄欖、鸡蛋和鱼类[1]。在美国,2021 年,每 250 毫升 20% 的成本约为 47 美元[4]

參考文獻

  1. ^ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Sepulveda, EA; Pak, A. Lipid Emulsion Therapy. January 2021. PMID 31751087. 
  2. ^ 2.0 2.1 2.2 2.3 2.4 2.5 Spray, JW. Review of Intravenous Lipid Emulsion Therapy.. Journal of infusion nursing : the official publication of the Infusion Nurses Society. 2016, 39 (6): 377-380. PMID 27828934. doi:10.1097/NAN.0000000000000194. 
  3. ^ Fettiplace, MR; Weinberg, G. Past, Present, and Future of Lipid Resuscitation Therapy.. JPEN. Journal of parenteral and enteral nutrition. September 2015, 39 (1 Suppl): 72S-83S. PMID 26187938. doi:10.1177/0148607115595979. 
  4. ^ Intralipid Prices, Coupons & Patient Assistance Programs. Drugs.com. [14 April 2021]. (原始内容存档于26 May 2021) (英语). 

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