Biochemical binding curves showing the characteristically sigmoidal curves generated by using the Hill equation to model cooperative binding. Each curve corresponds to a different Hill coefficient, labeled to the curve's right. The vertical axis displays the fraction of occupied ligand-binding sites on a protein receptor (), equal to ratio of the concentration of ligand-bound protein ([) to the total concentration of protein receptor (). The horizontal axis is the ratio of the ligand concentration producing half occupation () to the free ligand concentration ().
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