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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Trimerlizin I
Trimerlizin I
Identifikatori
EC broj	3.4.24.52
CAS broj	151125-16-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Trimerlizin I (EC 3.4.24.52, Trimeresurus metaloendopeptidaza I, hemoragična proteinaza HR1A, hemoragična metaloproteinaza HR1A, metaloproteinaza HR1A) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje dve veze, His¹⁰-Leu i Ala¹⁴-Leu, u lancu insulina B

Ova hemoragična endopeptidaza je prisutna u venumu zmije Trimeresurus flavoviridis.

Reference

^ Omori-Satoh, T. & Sadahiro, S. (1979). „Resolution of the major hemorrhagic component of Trimeresurus flavoviridis venom into two parts”. Biochim. Biophys. Acta. 580: 392—404. PMID 518906.
^ Yamakawa, Y. & Omori-Satoh, T. (1988). „The sites of cleavage in oxidized insulin-B chain by a hemorrhagic protease derived from the venom of the habu (Trimeresurus flavoviridis)”. Toxicon. 26: 227—231. PMID 3284004.
^ Takeya, H., Oda, K., Miyata, T., Omori-Satoh, T. and Iwanaga, S. (1990). „The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis”. J. Biol. Chem. 265: 16068—16073. PMID 2398046.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Trimerelysin+I на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Omori-Satoh, T. & Sadahiro, S. (1979). „Resolution of the major hemorrhagic component of Trimeresurus flavoviridis venom into two parts”. Biochim. Biophys. Acta. 580: 392—404. PMID 518906.

[2] Yamakawa, Y. & Omori-Satoh, T. (1988). „The sites of cleavage in oxidized insulin-B chain by a hemorrhagic protease derived from the venom of the habu (Trimeresurus flavoviridis)”. Toxicon. 26: 227—231. PMID 3284004.

[3] Takeya, H., Oda, K., Miyata, T., Omori-Satoh, T. and Iwanaga, S. (1990). „The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis”. J. Biol. Chem. 265: 16068—16073. PMID 2398046.

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