TRNK (guanin-N1-)-metiltransferaza

TRNK (guanin-N1-)-metiltransferaza
Identifikatori
EC broj	2.1.1.31
CAS broj	37256-99-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

TRNK (guanin-N1-)-metiltransferaza (EC 2.1.1.31, transfer ribonukleat guaninska 1-metiltransferaza, tRNK guaninska 1-metiltransferaza, S-adenozil-L-metionin:tRNK (guanin-1-N-)-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (guanin-N1-)-metiltransferaza.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + tRNK ${\displaystyle \rightleftharpoons }$ S-adenozil-L-homocistein + tRNK sa N₁-metilguaninom

Reference

1. Björk, G.R. & Svensson, I. (1969). „Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae”. Eur. J. Biochem. 9: 207—215. PMID 4896260. 
2. Glick, J.M., Averyhart, V.M. and Leboy, P.S. (1978). „Purification and characterization of two tRNA-(guanine)-methyltransferases from rat liver”. Biochim. Biophys. Acta. 518: 158—171. PMID 629973. CS1 одржавање: Вишеструка имена: списак аутора (веза)
3. Hurwitz, J., Gold, M. and Anders, M. (1964). „The enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. 3. Purification of soluble ribonucleic acid-methylating enzymes”. J. Biol. Chem. 239: 3462—3473. PMID 14245404. CS1 одржавање: Вишеструка имена: списак аутора (веза)
4. Smolar, N., Hellman, V. and Svennson, I. (1975). „Two transfer RNA (1-methylguanine) methylases from yeast”. Nucleic Acids Res. 2: 993—1004. PMID 1096087. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

• TRNA+(guanine-N1-)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)