Serinska racemaza
Serinska racemaza (EC 5.1.1.18, SRR) je enzim sa sistematskim imenom serin racemaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-serin D-serin
Ovaj enzim sadrži piridoksal fosfat.
Reference
- ^ Wolosker, H., Blackshaw, S. and Snyder, S.H. (1999). „Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission”. Proc. Natl. Acad. Sci. USA. 96: 13409—13414. PMID 10557334.
- ^ Wolosker, H., Sheth, K.N., Takahashi, M., Mothet, J.P., Brady, R.O., Jr., Ferris, C.D. and Snyder, S.H. (1999). „Purification of serine racemase: biosynthesis of the neuromodulator D-serine”. Proc. Natl. Acad. Sci. USA. 96: 721—725. PMID 9892700.
- ^ De Miranda, J., Santoro, A., Engelender, S. and Wolosker, H. (2000). „Human serine racemase: moleular cloning, genomic organization and functional analysis”. Gene. 256: 183—188. PMID 11054547.
- ^ Foltyn, V.N., Bendikov, I., De Miranda, J., Panizzutti, R., Dumin, E., Shleper, M., Li, P., Toney, M.D., Kartvelishvily, E. and Wolosker, H. (2005). „Serine racemase modulates intracellular D-serine levels through an α,β-elimination activity”. J. Biol. Chem. 280: 1754—1763. PMID 15536068.
Literatura
Spoljašnje veze
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