Serinska racemaza

Serinska racemaza
Identifikatori
EC broj5.1.1.18
CAS broj77114-08-0
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Serinska racemaza (EC 5.1.1.18, SRR) je enzim sa sistematskim imenom serin racemaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-serin D-serin

Ovaj enzim sadrži piridoksal fosfat.

Reference

  1. ^ Wolosker, H., Blackshaw, S. and Snyder, S.H. (1999). „Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission”. Proc. Natl. Acad. Sci. USA. 96: 13409—13414. PMID 10557334. 
  2. ^ Wolosker, H., Sheth, K.N., Takahashi, M., Mothet, J.P., Brady, R.O., Jr., Ferris, C.D. and Snyder, S.H. (1999). „Purification of serine racemase: biosynthesis of the neuromodulator D-serine”. Proc. Natl. Acad. Sci. USA. 96: 721—725. PMID 9892700. 
  3. ^ De Miranda, J., Santoro, A., Engelender, S. and Wolosker, H. (2000). „Human serine racemase: moleular cloning, genomic organization and functional analysis”. Gene. 256: 183—188. PMID 11054547. 
  4. ^ Foltyn, V.N., Bendikov, I., De Miranda, J., Panizzutti, R., Dumin, E., Shleper, M., Li, P., Toney, M.D., Kartvelishvily, E. and Wolosker, H. (2005). „Serine racemase modulates intracellular D-serine levels through an α,β-elimination activity”. J. Biol. Chem. 280: 1754—1763. PMID 15536068. 

Literatura

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