FMN reduktaza (NADH)

FMN reduktaza (NADH)
Identifikatori
EC broj	1.5.1.42
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

FMN reduktaza (NADH) (EC 1.5.1.42, NADH-FMN reduktaza, NADH-zavisna FMN reduktaza, NADH:FMN oksidoreduktaza, NADH:flavin oksidoreduktaza) je enzim sa sistematskim imenom FMNH₂:NAD⁺ oksidoreduktaza.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

FMNH₂ + NAD⁺ ${\displaystyle \rightleftharpoons }$ FMN + NADH + H⁺

Ova enzim često formira dvokomponentni sistem sa monooksigenazama. Za razliku od enzima EC 1.5.1.38, FMN reduktaze (NADPH), i EC 1.5.1.39, FMN reduktaze [NAD(P)H], ovaj enzim ima jaku preferenciju za NADH u odnosu na NADPH.

Reference

1. Duane, W. & Hastings, J.W. (1975). „Flavin mononucleotide reductase of luminous bacteria”. Mol. Cell. Biochem. 6: 53—64. PMID 47604. 
2. Gerlo, E. & Charlier, J. (1975). „Identification of NADH-specific and NADPH-specific FMN reductases in Beneckea harveyi”. Eur. J. Biochem. 57: 461—467. PMID 1175652. 
3. Uetz, T., Schneider, R., Snozzi, M. and Egli, T. (1992). „Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from "Chelatobacter" strain ATCC 29600”. J. Bacteriol. 174: 1179—1188. PMID 1735711. CS1 одржавање: Вишеструка имена: списак аутора (веза)
4. Izumoto, Y., Mori, T. and Yamamoto, K. (1994). „Cloning and nucleotide sequence of the gene for NADH:FMN oxidoreductase from Vibrio harveyi”. Biochim. Biophys. Acta. 1185: 243—246. PMID 8167139. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

• FMN+reductase+(NADH) на US National Library of Medicine Medical Subject Headings (MeSH)