Dinatrijum aurotiomalat

Dinatrijum aurotiomalat

Klinički podaci
Drugs.com	aurothiomalate.html Monografija
Identifikatori
CAS broj	12244-57-4^Y
ATC kod	none
PubChem	CID 71443
Hemijski podaci
Formula	C4H5AuNa2O5S
Molarna masa	408,091
SMILES O.[Na+].[Na+].[Au+].[O-]C(=O)CC([S-])C(=O)[O-]
InChI InChI=1S/C4H6O4S.Au.2Na.H2O/c5-3(6)1-2(9)4(7)8;;;;/h2,9H,1H2,(H,5,6)(H,7,8);;;;1H2/q;3*+1;/p-3^Y Key:YLQOAPBVYJCTPW-UHFFFAOYSA-K^Y

Dinatrijum aurotiomalat je organsko jedinjenje, koje sadrži 4 atoma ugljenika i ima molekulsku masu od 408,091 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	6
Broj donora vodonika	1
Broj rotacionih veza	3
Particioni koeficijent[1] (ALogP)	-3,1
Rastvorljivost[2] (logS, log(mol/L))	2,3
Polarna površina[3] (PSA, Å^2)	295,8

Reference

1. Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o. 
2. Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t. 
3. Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e. 

Literatura

• Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803. 
• Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799. 

Spoljašnje veze

• Disodium aurothiomalate