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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Diamin oksidaza
Diamin oksidaza
Identifikatori
EC broj	1.4.3.22
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Diamin oksidaza (EC 1.4.3.22, aminska oksidaza (nespecifična), CAO (nespecifična), Cu-sadržavajuća aminska oksidaza (nespecifična), bakarna aminska oksidaza (nespecifična), diaminska oksidaza (nespecifična), diamino oxhidraza (nespecifična), histaminaza, semikarbazid-senzitivna aminska oksidaza) je enzim sa sistematskim imenom histamin:kiseonik oksidoreduktaza (deaminacija).^[1]^[2]^[3]^[4]^[5] Ovaj enzim katalizuje sledeću hemijsku reakciju

histamin +H₂O + O₂

\rightleftharpoons

(imidazol-4-il)acetaldehid + NH₃ +H₂O₂

Ova grupa enzima oksiduje diamine, kao što je histamin, kao i neke primarne monoamine.

Reference

^ Zeller, E.A. (1963). „Diamine oxidases”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 8 (2nd изд.). New York: Academic Press. стр. 313—335.
^ Crabbe, M.J., Waight, R.D., Bardsley, W.G., Barker, R.W., Kelly, I.D. and Knowles, P.F. (1976). „Human placental diamine oxidase. Improved purification and characterization of a copper- and manganese-containing amine oxidase with novel substrate specificity”. Biochem. J. 155: 679—687. PMID 182134.
^ Chassande, O., Renard, S., Barbry, P. and Lazdunski, M. (1994). „The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter”. J. Biol. Chem. 269: 14484—14489. PMID 8182053.
^ Houen, G. (1999). „Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions”. APMIS Suppl. 96: 1—46. PMID 10668504.
^ Elmore, B.O., Bollinger, J.A. and Dooley, D.M. (2002). „Human kidney diamine oxidase: heterologous expression, purification, and characterization”. J. Biol. Inorg. Chem. 7: 565—579. PMID 12072962.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Diamine+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Zeller, E.A. (1963). „Diamine oxidases”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 8 (2nd изд.). New York: Academic Press. стр. 313—335.

[2] Crabbe, M.J., Waight, R.D., Bardsley, W.G., Barker, R.W., Kelly, I.D. and Knowles, P.F. (1976). „Human placental diamine oxidase. Improved purification and characterization of a copper- and manganese-containing amine oxidase with novel substrate specificity”. Biochem. J. 155: 679—687. PMID 182134.

[3] Chassande, O., Renard, S., Barbry, P. and Lazdunski, M. (1994). „The human gene for diamine oxidase, an amiloride binding protein. Molecular cloning, sequencing, and characterization of the promoter”. J. Biol. Chem. 269: 14484—14489. PMID 8182053.

[4] Houen, G. (1999). „Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions”. APMIS Suppl. 96: 1—46. PMID 10668504.

[5] Elmore, B.O., Bollinger, J.A. and Dooley, D.M. (2002). „Human kidney diamine oxidase: heterologous expression, purification, and characterization”. J. Biol. Inorg. Chem. 7: 565—579. PMID 12072962.

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