Dezoksiribonukleaza IV (fag-T4-indukovana)

Dezoksiribonukleaza IV (fag-T4-indukovana)
Identifikatori
EC broj	3.1.21.2
CAS broj	63363-78-0
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Dezoksiribonukleaza IV (fag-T4-indukovana) (EC 3.1.21.2, endodezoksiribonukleaza IV (fagom T4-indukovana), E. coli endonukleaza IV, endodezoksiribonukleaza, redoksiendonukleaza, deoksiriboendonukleaza, Escherichia coli endonukleaza II, endonukleaza II, DNK-adenin-transferaza) je enzim.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Endonukleolitičko razlaganje do 5'-fosfooligonukleotidnih krajnjih produkata

Ovaj enzim preferentno deluje na jednolančanu DNK.

Reference

1. Friedberg, E.C. & Goldthwait, D.A. (1969). „Endonuclease II of E. coli. I. Isolation and purification”. Proc. Natl. Acad. Sci. USA. 62: 934—940. PMID 4895219. 
2. Friedberg, E.C., Hadi, S.-M. and Goldthwait, D.A. (1969). „Endonuclease II of Escherichia coli. II. Enzyme properties and studies on the degradation of alkylated and native deoxyribonucleic acid”. J. Biol. Chem. 244: 5879—5889. PMID 4981786. CS1 одржавање: Вишеструка имена: списак аутора (веза)
3. Hadi, S.M. & Goldthwait, D.A. (1971). „Endonuclease II of Escherichia coli. Degradation of partially depurinated deoxyribonucleic acid”. Biochemistry. 10: 4986—4993. PMID 4944066. 
4. Sadowski, P.D. & Hurwitz, J. (1969). „Enzymatic breakage of deoxyribonucleic acid. I. Purification and properties of endonuclease II from T4 phage-infected Escherichia coli”. J. Biol. Chem. 244: 6182—6191. PMID 4310836. 

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

• Deoxyribonuclease+IV+(phage-T4-induced) на US National Library of Medicine Medical Subject Headings (MeSH)