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DTDP-4-amino-4,6-didezoksigalaktoza transaminaza
DTDP-4-amino-4,6-didezoksigalaktoza transaminaza
Identifikatori
EC broj	2.6.1.59
CAS broj	72560-97-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

DTDP-4-amino-4,6-didezoksigalaktoza transaminaza (EC 2.6.1.59, timidin difosfoaminodidezoksigalaktoza aminotransferaza, timidin difosfat 4-keto-6-dezoksi-D-glukoza transaminaza, WecE, dTDP-4,6-didezoksi-D-galaktoza:2-oksoglutarat aminotransferaza) je enzim sa sistematskim imenom dTDP-4,6-didezoksi-alfa-D-galaktoza:2-oksoglutarat aminotransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

dTDP-4-amino-4,6-didezoksi-alfa-D-galaktoza + 2-oksoglutarat

\rightleftharpoons

dTDP-4-dehidro-6-dezoksi-alfa-D-galaktoza + L-glutamat

Ovaj enzim je piridoksal-fosfatni protein.

Reference

^ Ohashi, H., Matsuhashi, M. and Matsuhashi, S. (1971). „Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis”. J. Biol. Chem. 246: 2325—2330. PMID 4928644.
^ Hwang, B.Y., Lee, H.J., Yang, Y.H., Joo, H.S. and Kim, B.G. (2004). „Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12”. Chem. Biol. 11: 915—925. PMID 15271350.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

DTDP-4-amino-4,6-dideoxygalactose+transaminase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Ohashi, H., Matsuhashi, M. and Matsuhashi, S. (1971). „Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis”. J. Biol. Chem. 246: 2325—2330. PMID 4928644.

[2] Hwang, B.Y., Lee, H.J., Yang, Y.H., Joo, H.S. and Kim, B.G. (2004). „Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12”. Chem. Biol. 11: 915—925. PMID 15271350.

[1]

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