Baeocistin

Baeocistin

Klinički podaci
Drugs.com	Monografija
Identifikatori
CAS broj	21420-58-6^Y
ATC kod	none
PubChem	CID 161359
ChemSpider	141741^Y
Hemijski podaci
Formula	C11H15N2O4P
Molarna masa	270,222
SMILES CNCCc1c[nH]c2cccc(OP(=O)(O)O)c12
InChI InChI=1S/C11H15N2O4P/c1-12-6-5-8-7-13-9-3-2-4-10(11(8)9)17-18(14,15)16/h2-4,7,12-13H,5-6H2,1H3,(H2,14,15,16)^Y Key:WTPBXXCVZZZXKR-UHFFFAOYSA-N^Y

Baeocistin je organsko jedinjenje, koje sadrži 11 atoma ugljenika i ima molekulsku masu od 270,222 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	5
Broj donora vodonika	4
Broj rotacionih veza	5
Particioni koeficijent[1] (ALogP)	1,5
Rastvorljivost[2] (logS, log(mol/L))	-1,7
Polarna površina[3] (PSA, Å^2)	104,4

Reference

1. Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o. 
2. Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t. 
3. Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e. 

Literatura

• Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803. 
• Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799. 

Spoljašnje veze

• Baeocystin