PROFILBARU.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

AMP—timidin kinaza
AMP—timidin kinaza
Identifikatori
EC broj	2.7.1.114
CAS broj	60440-28-0
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

AMP—timidin kinaza (EC 2.7.1.114, adenilat-nukleozidna fosfotransferaza) je enzim sa sistematskim imenom AMP:timidin 5'-fosfotransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

AMP + timidin

\rightleftharpoons

adenozin + dTMP

Dezoksipirimidinski kinazni kompleks indukovan virusom Herpes simplex katalizuje ovu reakciju, kao i reacije enzima EC 2.7.1.21 (timidin kinaza), EC 2.7.1.118 (ADP---timidin kinaza) i EC 2.7.4.9 (dTMP kinaza).

Reference

^ Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. (1982). „Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase”. Biochim. Biophys. Acta. 708: 99—103. PMID 6293576.
^ Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. (1981). „Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme”. J. Gen. Virol. 53: 247—255. PMID 6267178.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

AMP---thymidine+kinase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. (1982). „Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase”. Biochim. Biophys. Acta. 708: 99—103. PMID 6293576.

[2] Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. (1981). „Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme”. J. Gen. Virol. 53: 247—255. PMID 6267178.

[1]

[2]