(Acil-nosilac-protein) fosfodiestaraza

(acil-nosilac-protein) fosfodiestaraza
Identifikatori
EC broj	3.1.4.14
CAS broj	37288-21-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

(acil-nosilac-protein) fosfodiestaraza (EC 3.1.4.14, ACP hidrolijaza, ACP fosfodiesteraza, AcpH, (acil-nosilac-protein) 4'-pantetein-fosfohidrolaza, holo-(acil-nosilac-protein) 4'-pantetein-fosfohidrolaza) je enzim sa sistematskim imenom holo-(acil-nosilac protein) 4'-pantetein-fosfohidrolaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

holo-[acil-nosilac protein] + H₂O ${\displaystyle \rightleftharpoons }$ 4'-fosfopantetein + apo-[acil-nosilac protein]

Ovaj enzim razlaže acil-[acil-nosilac-protein] molekule sa acil lancima 6-16 ugljenika.

Reference

1. Sobhy, C. (1979). „Regulation of fatty acid synthetase activity. The 4′-phosphopantetheine hydrolase of rat liver”. J. Biol. Chem. 254: 8561—8566. PMID 224058. 
2. Vagelos, P.R. & Larrabee, A.R. (1967). „Acyl carrier protein. IX. Acyl carrier protein hydrolase”. J. Biol. Chem. 242: 1776—1781. PMID 4290442. 
3. Thomas, J. & Cronan, J.E. (2005). „The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization”. J. Biol. Chem. 280: 34675—34683. PMID 16107329. 

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

• (acyl-carrier-protein)+phosphodiesterase на US National Library of Medicine Medical Subject Headings (MeSH)