Ulcerative colitis
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease.[1] It is a long-term con
| Ulcerative colitis | |
|---|---|
 | |
| Endoscopic image of a colon affected by ulcerative colitis. The internal surface of the colon is blotchy and broken in places. Mild-moderate disease. | |
| Medical specialty | Gastroenterology |
| Symptoms | Abdominal pain, diarrhea mixed with blood, weight loss, fever, anemia,[1] dehydration, loss of appetite, fatigue, sores on the skin, urgency to defecate, inability to defecate despite urgency, rectal pain[2] |
| Complications | Megacolon, inflammation of the eye, joints, or liver, colon cancer[1][3] |
| Usual onset | 15–30 years or >60 years[1] |
| Duration | Long term[1] |
| Causes | Unknown[1] |
| Diagnostic method | Colonoscopy with tissue biopsies[1] |
| Differential diagnosis | Dysentery, Crohn's disease, ischemic colitis[4] |
| Treatment | Dietary changes, medication, surgery[1] |
| Medication | Sulfasalazine, mesalazine, steroids, immunosuppressants such as azathioprine, biological therapy[1] |
| Frequency | 2–299 per 100,000 |
| Deaths | 47,400 together with Crohn's (2015) |
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease.[1] It is a long-term condition that causes inflammation and ulcers of the colon and rectum.[1]
The main symptoms of the disease are abdominal pain and diarrhea mixed with blood.[1] Weight loss, fever, and anemia can also happen.[1] Symptoms come on slowly and can be either mild to severe.[1] Symptoms usually happen between periods of no symptoms and flares.[1] Problems may include an enlarged colon (megacolon), inflammation of the eye, joints, or liver, and colon cancer.[1][3]
The cause of UC is unknown.[1] Some possible causes include genetics, environment, and an overactive immune system.[1]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 "Ulcerative Colitis". NIDDK. September 2014. Retrieved 3 August 2016.
- ↑ "Ulcerative Colitis". Autoimmune Registry Inc. Archived from the original on 29 October 2018. Retrieved 15 June 2022.
- ↑ 3.0 3.1 Wanderås MH, Moum BA, Høivik ML, Hovde Ø (May 2016). "Predictive factors for a severe clinical course in ulcerative colitis: Results from population-based studies". World Journal of Gastrointestinal Pharmacology and Therapeutics. 7 (2): 235–241. doi:10.4292/wjgpt.v7.i2.235. PMC 4848246. PMID 27158539.
- ↑ Runge MS, Greganti MA (2008). Netter's Internal Medicine E-Book. Elsevier Health Sciences. p. 428. ISBN 9781437727722.
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.