ProSci is an Americanbiotechnology company with offices located in Poway, California.
The Poway site focuses on manufacturing antibodies[1] for use in research studies leading to diagnostics and therapy development. They specialize in producing a range of antibodies using polyclonal, monoclonal, and recombinant production techniques. ProSci has been a pioneer in the development of commercially available single domain antibodies (VHH – variable heavy chain) derived from camelid species, including llamas and alpacas.[2]
History
ProSci Incorporated was co-founded in 1998 by Yu Geng, M.D.[3][4] with the mission to develop neutralizing antibodies against emergent viruses. Their innovative approach using genetically engineered yeast strains and glycoproteins to mimic the HIV-1 glycan coat led to the development of neutralizing antibodies against HIV-1 glycans.
Early in 2020, ProSci was one of only a handful of companies that had antibodies available that recognized key proteins of the SARS-CoV-2 virus. Their reagents led to key discoveries on the mechanism of entry as well as neutralization of the SARS-CoV-2 virus.
Today, ProSci continues to offer tens of thousands of antibodies and custom antibody services to help researchers advance discoveries in the life sciences.
