She began her acting career in 1963 with the National Youth Theatre, later joining the Royal Shakespeare Company. She has since then appeared with several theatre companies in a wide variety of roles. She is widely regarded as one of the greatest British actresses of all time.
Mirren has also appeared in several series on television, notably as Inspector Jane Tennison in the Prime Suspect series, she was also acclaimed as QueenElizabeth I in the series Elizabeth I (2006).