MiR-122

miR-122 — микроРНК позвоночных. Она не встречается у беспозвоночных, у них также не найдены её близкие аналоги.[1]

miR-122 сильно выражена в печени, где она выполняет роль регулятора жирнокислотного метаболизма. Уменьшение уровня miR-122 связано с гепатоцеллюлярной карциномой. miR-122 выполняет важную роль в репликации вируса гепатита C; экспериментальный препарат Миравирсен использует это свойство.

Структура

3'-UGUUUGUGGUAACAGUGUGAGGU-5'

Ссылки

  1. ↑ miRBase. Дата обращения: 10 мая 2017. Архивировано 9 мая 2017 года.

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