Factor IX

Structura terțiară

Factorul IX (sau factorul Christmas, EC 3.4.21.22) este o serin proteză implicată în cascada coagulării. Deficitul său produce hemofilia B. A fost descoperită în anul 1952 și numele provine de la Stephen Christmas, un băiat care suferea de hemofilie din cauza lipsei acestui factor de coagulare.[1]

Pentru tratamentul hemofiliei B, se află pe lista medicamentelor esențiale ale Organizației Mondiale a Sănătății.[2]

Note

  1. ^ Biggs R, Douglas AS, Macfarlane RG, Dacie JV, Pitney WR (). „Christmas disease: a condition previously mistaken for haemophilia”. British Medical Journal. 2 (4799): 1378–82. doi:10.1136/bmj.2.4799.1378. PMC 2022306 Accesibil gratuit. PMID 12997790. 
  2. ^ Organizația Mondială a Sănătății (). World Health Organization model list of essential medicines: 21st list 2019 (PDF) (în engleză). Geneva: World Health Organization. hdl:10665/325771 Accesibil gratuit. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. 

Vezi și


v • d • m
Antihemoragice (ATC B02)
Antihemoragice
(coagulare)
Sistemice
Altele
Carbazocrom  • Etamsilat  • Fostamatinib  • Avatrombopag  • Eltrombopag  • Romiplostim
Locale (hemostatice)
Alginat de calciu  • Adrenalină  • Alaun de potasiu  • Bureți cu gelatină  • Colagen  • Trombină
Antifibrinolitice

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