Cerivastatina

Cerivastatina
Alerta sobre risco à saúde
Nome IUPAC (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid
Identificadores
Número CAS 145599-86-6
PubChem 446156
DrugBank APRD00102
ChemSpider 393588
Código ATC C10AA06
Propriedades
Fórmula química C26H34FNO5
Massa molar 459.52 g mol-1
Farmacologia
Meia-vida biológica 2 a 3 h
Página de dados suplementares
Estrutura e propriedades n, εr, etc.
Dados termodinâmicos Phase behaviour
Solid, liquid, gas
Dados espectrais UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a
materiais sob condições normais de temperatura e pressão

Referências e avisos gerais sobre esta caixa.
Alerta sobre risco à saúde.


Cerivastatina é um fármaco membro da classe das estatinas, usado para tratar a hipercolesterolemia e prevenir doenças cardiovasculares. Foi comercializado pela empresa farmacêutica Bayer AG no final dos anos 1990, competindo com a altamente bem sucedida atorvastatina (Lipitor) da Pfizer. A cerivastatina foi voluntariamente retirado do mercado mundial em 2001, devido a relatos de casos fatais de rabdomiólise[1].

Referências

  1. «Suspensão temporária da comercialização do Lipobay® (cerivastatina)». 9 de agosto de 2001. Consultado em 24 de junho de 2010 

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