Proof var lenge venn og pressesjef for Eminem, med navn som «Big Proof», «P», «Dirty Harry» og «Oil Can Harry». Han var også Eminems forlover.
Proof begynte sin karriere i en freestyle-turnering arrangert av en hiphop-organisasjon i Detroit. Det var der han møtte og ble venner med flere av medlemmene av det som senere ble D12. Han ble skutt og drept 11. april 2006.[4]
^«The true story behind the killing of Eminem's friend Proof». the Guardian (på engelsk). 21. mai 2006. Besøkt 25. januar 2021. «DeShaun Dupree Holton, aka P, Big Proof, Proof or Derty Harry [sic], died at 4.30am on 11 April at the age of 32. That night, he had been at the CCC club, an after-hours establishment on a sketchy stretch of East 8 Mile road in Detroit, where he and a few friends were playing pool after a night of party-hopping. He found himself in an argument with Keith Bender Jr, a 35-year-old Desert Storm veteran, allegedly during a game of pool. An altercation ensued, attracting the attention of the club's bouncer, Mario Etheridge, who is Bender's cousin. Within a few minutes, both Bender and Proof were fatally shot: a bullet to Bender's face took his life eight days later (the same morning that Proof was buried), while Proof was killed instantly by two shots to his back and one to the back of his head.»