Jabatan Keselamatan Utama Reich (Bahasa Jerman: Reichssicherheitshauptamt) atau RSHA adalah sebuah organisasi bawahan kepada Heinrich Himmler selaku Chef der Deutschen Polizei (Ketua Polis Jerman) dan Reichsführer-SS, ketua 'SS' Parti Nazi. Tugas utama organisasi tersebut ialah melawan semua "musuh-musuh Reich" samada didalam dan diluar sempadan Jerman Nazi.
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