D-lisopina deidrogenasi

D-lisopina deidrogenasi
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Numero EC1.5.1.16
ClasseOssidoreduttasi
Nome sistematico
N2-(D-1-carbossietil)-L-lisina:NADP+ ossidoreduttasi (L-lisina-formante)
Altri nomi
D-lisopina sintetasi; lisopina deidrogenasi; D(+)-lisopina deidrogenasi; 2-N-(D-1-carbossietil)-L-lisina:NADP+ ossidoreduttasi (L-lisina-formante)
Banche datiBRENDA, EXPASY, GTD, PDB (RCSB PDB PDBe PDBj PDBsum)
Fonte: IUBMB

La D-lisopina deidrogenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione:

N2-(D-1-carbossietil)-L-lisina + NADP+ + H2O L-lisina + piruvato + NADPH + H+

Nella reazione inversa, un certo numero di L-aminoacidi possono agire al posto della L-lisina, ed il 2-ossobutanoato e, in misura minore, il gliossilato possono agire al posto del piruvato.

Bibliografia

  • Otten, L.A.B.M., Vreugdenhil, D. and Schilperoort, R.A., Properties of D(+)-lysopine dehydrogenase from crown gall tumour tissue, in Biochim. Biophys. Acta, vol. 485, 1977, pp. 268–277, Entrez PubMed 21695.

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