Cellule lymphoïde progénitrice

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La cellule lymphoïde progénitrice (ou CLP, common lymphoid progenitor) est une cellule issue de la cellule souche hématopoïétique (CSH) tout comme la cellule progénitrice myéloïde.

La cellule lymphoïde progénitrice va produire, en se divisant, la lignée lymphoïde. Elle se différence en plusieurs types de lymphocytes : le lymphocyte T, le lymphocyte B, le lymphocyte NK et la cellule lymphoïde innée (CLI)[1].

La prolifération et la survie des cellules lymphoïdes progénitrices est essentielle pour la génération d'un nombre suffisant de lymphocytes matures[2].

Liens externes

Notes et références

  1. ↑ (en) Umit Sahiner, Mübeccel Akdis et Cezmi A. Akdis, « 1 - Introduction to Mechanisms of Allergic Diseases », dans Allergy Essentials (Second Edition), Elsevier, (ISBN 978-0-323-80912-2, DOI 10.1016/b978-0-323-80912-2.00001-9, lire en ligne), p. 1–24
  2. ↑ (en) Sung-Yun Pai et Luigi D. Notarangelo, « Chapter 51 - Congenital Disorders of Lymphocyte Function », dans Hematology (Seventh Edition), Elsevier, (ISBN 978-0-323-35762-3, DOI 10.1016/b978-0-323-35762-3.00051-2, lire en ligne), p. 710–723.e3

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