ADN polymérase epsilon

L'ADN polymérase ε, ou pol ε, est une ADN polymérase présente chez les eucaryotes et qui intervient dans les processus de réplication de l'ADN et de réparation de l'ADN[1]. Cette enzyme est constituée de quatre sous-unités : POLE, POLE2, POLE3 et POLE4 ; la sous-unité POLE est la sous-unité catalytique centrale.

Notes et références

  1. ↑ (en) Deqi HUANG, Helmut POSPIECH, Tapio KESTI et Juhani E. SYVÄOJA, « Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase ε », Biochemical Journal, vol. 339, no Pt 3,‎ , p. 657-665 (PMID 10215605, PMCID 1220202, lire en ligne)

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