کارسینوم سلول آسینار لوزالمعده

کارسینوم سلول آسینار لوزالمعده
نام‌های دیگرکارسینوم سلول آسینار
عکاسی ریزنگاری کارسینوم سلول آسینار لوزالمعده با استفاده از رنگ‌آمیزی هماتوکسیلین-ائوزین.
تخصصسرطان‌شناسی
طبقه‌بندی و منابع بیرونی
بروز نسبی نئوپلاسم‌های گوناگون لوزالمعده.[۱]

کارسینوم سلول آسینار لوزالمعده (انگلیسی: Acinar cell carcinoma of the pancreas) یا به اختصار «ACC» نوعی نادر و بدخیم از سرطان لوزالمعده است. این تومور، ۵٪ از کل تومورهای بخش برون‌ریز لوزالمعده را تشکیل می‌دهد و دومین نوع شایع سرطان لوزالمعده محسوب می‌شود.[۲] پیش‌آگهی این سرطان، جدی و غیرقابل پیش‌بینی است.

این نوع سرطان در مردان شایع‌تر از زنان است و سن متوسط تشخیص بیماری ۶۰ است.[۳] علائم بیماری غیر اختصاصی و شامل کاهش وزن است. تظاهر کلاسیک بیماری، سه علامت مشهور به «علائم سه‌گانهٔ اشمیت» است که شامل ندول‌های زیرپوستی (به‌دلیل نکروز چربیدرد مفصلی (به سبب رها شدن لیپاز)[۳] و ائوزینوفیلی است.[۴]

کارسینوم سلول آسینار لوزالمعده معمولاً بزرگ است و تا ۱۰ سانتی‌متر رشد می‌کند و قوام آن در مقایسه با آدنوکارسینوم لوزالمعده نرم‌تر است و فاقد استرومای متراکم است. این تومور ممکن است در هر جایی از لوزالمعده ایجاد شود.[۳]

درمان اصلی این سرطان، جراحی است.

جستارهای وابسته

منابع

  1. Wang Y, Miller FH, Chen ZE, Merrick L, Mortele KJ, Hoff FL; et al. (2011). "Diffusion-weighted MR imaging of solid and cystic lesions of the pancreas". Radiographics. 31 (3): E47-64. doi:10.1148/rg.313105174. PMID 21721197.{{cite journal}}: نگهداری یادکرد:نام‌های متعدد:فهرست نویسندگان (link)
    Diagram by Mikael Häggström, M.D.
  2. Tobias Jeffrey S., Hochhauser, Daniel, Cancer and its Management, p. 276, 2010 (6th edn), شابک ‎۱۱۱۸۷۱۳۲۵۷, 9781118713259
  3. ۳٫۰ ۳٫۱ ۳٫۲ Von Hoff": Daniel D. Von Hoff, Douglas Brian Evans, Ralph H. Hruban, eds. Pancreatic Cancer, 2005, Jones & Bartlett Learning, شابک ‎۰۷۶۳۷۲۱۷۸۶, 9780763721787
  4. Jang, SH.; Choi, SY.; Min, JH.; Kim, TW.; Lee, JA.; Byun, SJ.; Lee, JW. (Feb 2010). "[A case of acinar cell carcinoma of pancreas, manifested by subcutaneous nodule as initial clinical symptom]". Korean J Gastroenterol. 55 (2): 139–43. doi:10.4166/kjg.2010.55.2.139. PMID 20168061.

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